Answer:
I
S
S

We have spotted ISS (3 Letters) a total of 386 times in our database. Below you may see the clues associated with ISS and also when and where was it last seen:

Referring crossword puzzle clues

Usage among publishers:

  • Newsday: Nov 14, 2025
  • LA Times: Jul 31, 2025
  • Newsday: Mar 21, 2025
  • New York Times: Dec 26, 2024
  • Wall Street Journal: Feb 16, 2024
  • Eugene Sheffer: Dec 15, 2023
  • Wall Street Journal: Nov 28, 2023